Characterization of proximal pulmonary artery cells in chronic thromboembolic pulmonary hypertension patients
نویسندگان
چکیده
Patient Cause of PH Age (years) Gender mPAP (mm Hg) RAP (mm Hg) CO (L.min) TPR (dyne.sec.cm) 1 IPAH 27 F 55 13 2,9 1733 2 IPAH 56 M (64) (15) (5.6) (923) 3 IPAH 42 M 30 NA 9,2 264 4 EAA 44 M 33 22 6,2 422 5 COPD 59 M 30 15 7,2 330 6 sarcoidosis 44 M 48 11 NA NA 7 IPAH 41 F (60) (13) (3.2) (1481) 8 IPAH 37 F 45 14 5,4 662 9 IPF 64 M 51 8 5,1 805 10 EAA 52 M 43 11 4,5 764 11 PAH-CHD 45 V (71) (14) (2.4) (2328) 12 bronchiectasis 61 M 37 11 6,3 470
منابع مشابه
Drug Therapy in Patients with Chronic Thromboembolic Pulmonary Hypertension
Background: Chronic Thromboembolic Pulmonary Hypertension (CTEPH) results from the obstruction of predominantly major pulmonary vessels by organized blood clots and is one of the causes of pulmonary hypertension. The disease is still underdiagnosed and the true prevalence is not clear. The objective of this study was to determine the clinical characteristics and current management of patients w...
متن کاملCharacterization of proximal pulmonary arterial cells from chronic thromboembolic pulmonary hypertension patients
BACKGROUND Chronic thromboembolic pulmonary hypertension (CTEPH) is associated with proximal pulmonary artery obstruction and vascular remodeling. We hypothesized that pulmonary arterial smooth muscle (PASMC) and endothelial cells (PAEC) may actively contribute to remodeling of the proximal pulmonary vascular wall in CTEPH. Our present objective was to characterize PASMC and PAEC from large art...
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While pulmonary thromboembolism is common, thromboembolic pulmonary hypertension is very rare. The present case is a 35 year old woman with chronic thromboembolic pulmonary hypertension, who presented with severe dyspnea and leg edema, following an earlier thrombotic event of 10 years earlier, after her her second childbearing. She also had a history of the first childbearing complicated with c...
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PURPOSE We aimed to determine the correlation between flow characteristics of the proximal pulmonary arteries and vena cava obtained by 3.0 T phase-contrast magnetic resonance imaging (MRI) and hemodynamic characteristics by right heart catheterization in patients with chronic thromboembolic pulmonary hypertension. MATERIALS AND METHODS Twenty consecutive patients with chronic thromboembolic ...
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